A SECRET WEAPON FOR CONOLIDINE ALKALOID FOR CHRONIC PAIN

Most not too long ago, it's been discovered that conolidine and the above derivatives act over the atypical chemokine receptor 3 (ACKR3. Expressed in very similar parts as classical opioid receptors, it binds to a big range of endogenous opioids. Not like most opioid receptors, this receptor acts to be a scavenger and would not activate a next mess